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3rd-Party & Clinically Tested

3rd-Party Lab Tested

Every batch tested for purity & label accuracy โ†’

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GLP-1's New Bestie:
Nutrient Support Made Easy

  • โœ“ 23g protein + 8g collagen in one 100ml shot
  • โœ“ Fills nutrient gaps GLP-1s create (hair, muscle, energy)
  • โœ“ Supports digestion, reduces nausea & everyday wellness

Pack Size

โœ… Limited Time Discount Auto-Applied

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365-Day Money-Back Guarantee
๐Ÿ”ฌ
Clinically & 3rd Party Tested
๐Ÿ’ณ
HSA/FSA Eligible

You're on a GLP-1 and it's working โ€” but your body is paying a tax. Hair shedding. Muscle loss. Constipation. Exhaustion. Nausea on shot day. You're spending $150โ€“$300/month on a stack of supplements that barely works.

One Shot consolidates everything into one 100ml shot: 23g clinical-dose protein, 8g collagen, 5g acacia fiber, 500mg ginger root, full-spectrum B vitamins, iron, zinc, magnesium, and electrolytes. One shot. 30 seconds. Done.

Serving Size: 1 bottle (100ml) | Servings Per Container: 1

Calories 115 ยท Protein 23g (46% DV) ยท Total Carbohydrate 7g (3% DV) ยท Dietary Fiber 5g (18% DV) ยท Total Sugars 0g ยท Vitamin C 90mg (100%) ยท Vitamin D3 1000 IU (125%) ยท Vitamin B6 5mg (294%) ยท Folate 400mcg (100%) ยท B12 500mcg (20,833%) ยท Iron 14mg (78%) ยท Zinc 11mg (100%) ยท Magnesium 100mg (24%) ยท Sodium 500mg (22%) ยท Potassium 300mg (6%)

Proprietary Blend: Collagen Peptides 8g ยท Whey Isolate 9g ยท Hydrolyzed Whey 6g ยท EAA Blend 3g ยท Ginger Root Extract 500mg ยท Hyaluronic Acid 120mg

Other: Filtered water, natural flavors, citric acid, monk fruit extract, allulose, gellan gum. Contains: Milk.

๐Ÿ’‡ Hair Shedding: Iron bisglycinate + zinc + B vitamins + 8g collagen โ€” the full machinery your hair follicles are starving for.

๐Ÿ’ช Muscle Loss: 23g complete protein + EAA blend dosed above the muscle-protein-synthesis threshold.

๐Ÿšฝ Constipation: 5g acacia prebiotic fiber supports regular digestion. No Miralax needed.

๐Ÿคข Nausea: 500mg ginger root extract (5% gingerols) โ€” the clinically studied dose.

โšก Fatigue: B12 (500mcg), B6, iron, magnesium, sodium + potassium electrolytes.

โœจ Ozempic Face: 8g collagen peptides + 120mg hyaluronic acid support skin structure and hydration.

Shake well. Drink one 100ml bottle daily, preferably in the morning. Can be taken on an empty stomach. On shot days, take in the morning before your injection for best nausea support.

Tastes Like

๐Ÿ‹Fresh & Clean
๐ŸซšLight & Smooth
๐ŸŒฟMildly Herbal

Packed With

  • ๐ŸฅฉClinical-Dose Protein (23g)
  • ๐ŸฆดCollagen Peptides (8g)
  • ๐ŸŒพPrebiotic Acacia Fiber (5g)
  • ๐ŸซšGinger Root Extract (500mg)
  • โšกFull-Spectrum B Vitamins
  • ๐Ÿ’งElectrolytes (Na + K + Mg)
  • โœจHyaluronic Acid (120mg)
  • ๐Ÿ”ฌAll 9 Essential Amino Acids
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The GLP-1 Side Effect Solver

7 Ways One Shot Has You Covered

GLP-1 medications are powerful โ€” but they come with a nutrient tax. Every ingredient in One Shot is dosed at clinically meaningful levels to address the exact deficiencies your medication creates.

Hair Shedding
01

Hair Shedding

Your Hair Is Falling Out. Here's Why.

Hair loss affects up to 71% of GLP-1 users within the first 3 months. The cause isn't the drug โ€” it's the nutrient deficiency the drug creates by reducing your appetite and food intake.

"I lost 30 lbs and half my hair. Nobody warned me about this."
๐Ÿ”ฌ Iron 14mg + Zinc 11mg + B12 500mcg + Collagen 8g
02

Muscle Loss

You're Losing Fat. And Muscle.

Up to 39% of weight lost on GLP-1s can be lean muscle mass โ€” not fat. This is the hidden cost nobody talks about. The result: "skinny fat" โ€” lower weight, but less muscle tone and slower metabolism.

"Down 38 lbs but I look deflated, not fit."
๐Ÿ”ฌ Protein 23g + EAA Blend 3g
Muscle Loss
Ozempic Face
03

Ozempic Face

The Skin You're Losing With The Weight.

Rapid fat loss depletes the structural proteins that keep skin firm and joints lubricated. The result: hollow cheeks, crepey skin, and joint aches. Collagen and hyaluronic acid are the clinical answer.

"I look 10 years older. I lost the weight but lost my face."
๐Ÿ”ฌ Collagen 8g + Hyaluronic Acid 120mg
04

Constipation

The Side Effect Nobody Talks About.

GLP-1s slow gastric emptying โ€” which is great for appetite control, but brutal for your gut. Up to 24% of users report chronic constipation. Acacia fiber is the prebiotic gastroenterologists reach for first.

"I hadn't gone in 5 days. This was the only thing that helped."
๐Ÿ”ฌ Acacia Fiber 5g (18% DV)
Constipation
Shot Day Nausea
05

Shot Day Nausea

The Morning After Your Injection.

Nausea is the #1 reason people abandon GLP-1 therapy. Most supplements use 50mg of ginger as label decoration. We use the clinical dose โ€” the same one used in chemotherapy nausea trials.

"Shot day used to ruin my whole morning. Not anymore."
๐Ÿ”ฌ Ginger Root 500mg (5% gingerols)
06

Fatigue & Brain Fog

The 3pm Crash Isn't Laziness.

When you're barely eating, electrolyte and B vitamin depletion hits fast. The fatigue and brain fog you're experiencing are biochemical โ€” and they're fixable with the right doses of the right nutrients.

"I was exhausted by noon every day. This fixed it in a week."
๐Ÿ”ฌ Electrolytes 900mg + Methylated B-Complex
Fatigue
The Stack Problem
07

The Stack Problem

Stop Counting Out 8 Pills.

The average GLP-1 user spends $150โ€“$300/month on 7+ separate supplements. Most are underdosed. All are inconvenient. None are designed for GLP-1 users. One Shot replaces all of them.

"I was spending $200/month on a stack that barely worked."
๐Ÿ”ฌ One Shot replaces 7+ supplements

3rd Party & Clinically Tested

Benefits GLP-1 Users Love

On a GLP-1 or weight loss journey? Here's why adding One Shot to your morning routine can make a real difference โ€” without adding complexity.

๐Ÿ’‡
of GLP-1 users report shedding
7.1%
Keeps Your Hair
Iron bisglycinate + zinc + B-complex + 8g collagen โ€” the full machinery your hair follicles are starving for.
๐Ÿ’ช
of GLP-1 weight loss can be lean mass
39%
Preserves Muscle
23g complete protein + EAA blend dosed above the muscle-protein-synthesis threshold. Works with the drug.
โœจ
collagen + hyaluronic acid
8g + 120mg
Fights Ozempic Face
The exact oral doses clinical studies use for skin elasticity, hydration, and joint comfort.
๐Ÿšฝ
acacia senegal fiber
5g
Ends Constipation
The prebiotic gastroenterologists reach for first โ€” ferments slowly, no gas, no Miralax.
๐Ÿคข
ginger root (5% gingerols)
500mg
Survives Shot Day
The same clinical dose used in chemotherapy nausea trials. Not 50mg of label decoration.
โšก
sodium / potassium / magnesium
500/300/100mg
Kills the 3pm Crash
Real electrolyte doses + methylated B-complex for the ~40% of women who can't process synthetic B vitamins.

One bottle. Six problems solved. 30 seconds.

3rd-party tested ยท GMP certified ยท HSA/FSA eligible ยท 365-day guarantee

Replace Your Entire Stack

Stop spending $200/month on 8 separate supplements that don't work together.

Your Current Stack
Protein Powder$45/mo
Collagen Supplement$35/mo
Fiber Supplement$20/mo
Ginger Capsules$15/mo
B-Complex Vitamin$18/mo
Iron Supplement$12/mo
Electrolyte Powder$25/mo
Hyaluronic Acid$22/mo
Total Monthly Cost$192/mo
One Shot Daily Shot
โœ“ Protein (23g whey isolate)Included
โœ“ Collagen (8g Type I & III)Included
โœ“ Acacia Fiber (5g)Included
โœ“ Ginger Root (500mg)Included
โœ“ Methylated B-ComplexIncluded
โœ“ Iron Bisglycinate (14mg)Included
โœ“ Electrolytes (Na+K+Mg)Included
โœ“ Hyaluronic Acid (120mg)Included
Total Monthly CostFrom $126/mo

YOUR TIMELINE

What Happens When You Start

Great health doesn't happen overnight โ€” but it does happen daily.

Ginger ยท 500mg

Nausea Relief Begins

500mg ginger root extract starts working immediately. Most users notice reduced shot-day nausea within the first 1โ€“2 uses.

๐ŸŒฟ
๐Ÿ“…Day 1
๐Ÿ“…Week 1
โšก
B12 ยท Iron ยท Electrolytes

Energy Returns

Electrolytes and methylated B vitamins begin restoring cellular energy. The 3pm crash starts to lift.

Acacia Fiber ยท 5g

Digestion Improves

Acacia fiber reaches steady-state in your gut microbiome. Constipation resolves for most users by day 10โ€“14.

๐ŸŒฑ
๐Ÿ“…Week 2
๐Ÿ“…Wk 3โ€“4
๐Ÿ’†
Iron ยท Zinc ยท Biotin

Hair Shedding Slows

Iron, zinc, and B vitamins reach tissue saturation. Most users notice significantly less shedding in the shower by week 4.

Collagen ยท Protein ยท HA

Skin & Muscle Visible

Collagen and protein synthesis effects become visible. Skin looks firmer, muscle tone improves, "GLP-1 face" starts to reverse.

โœจ
๐Ÿ“…Mo 2
๐Ÿ“…Mo 3+
๐Ÿ†
Full Stack ยท 1 Bottle

Your New Normal

Full nutrient saturation. Hair growing back. Energy stable. Skin and muscle maintained. GLP-1 working without the side effects.

๐ŸŒฟ
Day 1

Nausea Relief Begins

500mg ginger root extract starts working immediately. Most users notice reduced shot-day nausea within the first 1โ€“2 uses.

โšก
Week 1

Energy Returns

Electrolytes and methylated B vitamins begin restoring cellular energy. The 3pm crash starts to lift.

๐ŸŒฑ
Week 2

Digestion Improves

Acacia fiber reaches steady-state in your gut microbiome. Constipation resolves for most users by day 10โ€“14.

๐Ÿ’†
Wk 3โ€“4

Hair Shedding Slows

Iron, zinc, and B vitamins reach tissue saturation. Most users notice significantly less shedding in the shower by week 4.

โœจ
Mo 2

Skin & Muscle Visible

Collagen and protein synthesis effects become visible. Skin looks firmer, muscle tone improves, "GLP-1 face" starts to reverse.

๐Ÿ†
Mo 3+

Your New Normal

Full nutrient saturation. Hair growing back. Energy stable. Skin and muscle maintained. GLP-1 working without the side effects.

Recommended by Clinicians

1,722 clinicians share One Shot on FrontrowMD without compensation.

RT
Dr. Rachel Torres, MD
Board-Certified Internal Medicine ยท GLP-1 Prescriber
"I prescribe GLP-1 medications daily and the nutrient depletion is real. One Shot is the first product I've seen that actually addresses the clinical picture โ€” iron bisglycinate instead of ferrous sulfate, methylated B vitamins, clinical-dose ginger. I recommend it to every patient I start on semaglutide."
GLP-1 Specialist
AC
Dr. Amanda Chen, PharmD
Clinical Pharmacist ยท Metabolic Health Specialist
"The formulation is impressive. They're using the right forms โ€” bisglycinate iron doesn't cause GI upset, 5-MTHF instead of folic acid for the MTHFR population, and the ginger dose is actually therapeutic. This isn't a marketing product. It's a clinical product."
Pharmacist
JN
Jessica Nguyen, RDN
Registered Dietitian Nutritionist ยท Weight Management
"My GLP-1 patients were coming in with hair loss, fatigue, and muscle loss โ€” all textbook signs of protein and micronutrient deficiency. One Shot addresses every single one of those gaps in a single serving. It's become my first recommendation for every new GLP-1 patient."
Registered Dietitian
โ˜…โ˜…โ˜…โ˜…โ˜… 4.8 stars

Join 50,000+ GLP-1 Users Who Made the Switch

๐Ÿ›ก๏ธ

365-Day Money-Back Guarantee

We're so confident One Shot will work for you that we offer a full year to try it. If your hair isn't improving, your energy isn't back, or you just don't love it โ€” one email and you get a full refund. No forms. No hoops.

365-Day Money-Back

A full year to try it. No questions asked. One email to our support team.

Cancel Any Time

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No Hoops

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Frequently Asked Questions

Orders ship within 1โ€“2 business days. Standard delivery is 3โ€“5 business days. Subscribe & Save orders qualify for free expedited shipping on your first order.
One Shot is designed to complement GLP-1 medications, not interfere with them. The formula contains no stimulants, no hormones, and no ingredients known to interact with semaglutide or tirzepatide. As always, consult your prescribing physician if you have specific concerns.
Yes. One Shot is specifically formulated to complement GLP-1 medications. It contains no stimulants, no hormones, and no ingredients known to interact with semaglutide (Ozempic/Wegovy) or tirzepatide (Zepbound/Mounjaro). The formula works alongside your medication to replenish the nutrients your GLP-1 depletes.
On shot days, we recommend taking One Shot in the morning before your injection for the best nausea support โ€” the 500mg ginger root extract works best when it's already in your system. On non-injection days, take it any time in the morning. It can be taken on an empty stomach.
One Shot is specifically designed for people with reduced appetite and sensitive stomachs. The ginger extract helps with nausea, and the iron bisglycinate form we use is the only form that doesn't cause GI side effects. The formula is gentle enough to take on an empty stomach.
Most users notice improved energy and reduced nausea within the first 3โ€“7 days. Hair shedding typically slows noticeably by weeks 3โ€“4. Skin and muscle improvements build over 4โ€“8 weeks of consistent use.
No. The nutrient depletion pattern is consistent across all GLP-1 medications. One Shot addresses the underlying mechanism โ€” nutrient deficiency from reduced intake โ€” not the specific drug.
We offer a 365-day money-back guarantee. If you're not satisfied for any reason, contact our support team for a full refund. One email. No forms. No hoops.

Replace 7 Supplements With One Shot

The Complete GLP-1 Morning,
In 30 Seconds.

Stop counting out 8 pills. Stop gagging on chalky shakes. Stop spending $200/month on a stack that doesn't work. One Shot has everything your body needs while on a GLP-1.

Save 50% + FREE Shipping โ†’

365-Day Money-Back Guarantee ยท Cancel Anytime ยท HSA/FSA Eligible

Supplement Facts

Supplement Facts

Serving Size: 1 bottle (100ml)

Servings Per Container: 1

Calories115
% Daily Value*
Total Carbohydrate7g ยท 3%
  Dietary Fiber (Acacia Senegal)5g ยท 18%
  Total Sugars0g
Protein (Whey Isolate + Hydrolyzed + Collagen)23g ยท 46%
Vitamin C (ascorbic acid)90mg ยท 100%
Vitamin D3 (cholecalciferol)1000 IU ยท 125%
Vitamin B6 (pyridoxal-5-phosphate)5mg ยท 294%
Folate (L-5-methyltetrahydrofolate)400mcg DFE ยท 100%
Vitamin B12 (methylcobalamin)500mcg ยท 20,833%
Pantothenic Acid10mg ยท 200%
Iron (ferrous bisglycinate chelate)14mg ยท 78%
Zinc (bisglycinate)11mg ยท 100%
Magnesium (citrate)100mg ยท 24%
Sodium (citrate)500mg ยท 22%
Potassium (citrate)300mg ยท 6%
Proprietary Blend:
Collagen Peptides (Type I & III, hydrolyzed)8g
Native Whey Protein Isolate9g
Hydrolyzed Whey Protein Isolate6g
EAA Blend (all 9 essential amino acids)3g
Ginger Root Extract (5% gingerols)500mg
Hyaluronic Acid (sodium hyaluronate)120mg

Other ingredients: Filtered water, natural flavors, citric acid, monk fruit extract , allulose, gellan gum, potassium sorbate. Contains: Milk.

*Percent Daily Values are based on a 2,000 calorie diet.

3rd-Party Lab Tested for Purity & Label Accuracy

Manufactured in GMP-certified, FDA-registered facilities

ONE SHOT โ€” 28-Pack (Full Month)
Subscribe & Save ยท $126/mo